Buchholz stands at 6 feet 4 inches tall and weighs 220 lbs. He bats and throws right-handed. He did not go to college. He lives in Springfield, PA during the offseason.
Buchholz started out as a minor leaguer for the Philadelphia Phillies. In 2003, he was dealt with Ezequiel Astacio and Brandon Duckworth to the Astros for all-star closer Billy Wagner. Originally forgotten by many fans due to Astacio and Duckworth both quickly being brought up to the majors, Buchholz proceeded to impress scouts in the minors, showing promise for the future. After going 6-0 with a 4.81 ERA in 20 games for the Astros Triple A Affiliate Round Rock Express in 2005, Buchholz was called up to the Astros main roster in the 2006 season.
His first major success came in his second major league appearance in what was almost a complete-game one-hit shutout against the Pittsburgh Pirates. The real result occurred when second baseman Eric Bruntlett double-clutched the ball before throwing, allowing runner Chris Duffy to reach first base safely. After Jack Wilson hit a single off Buchholz, Astros manager Phil Garner pulled him out of the game and brought in closer Brad Lidge, who struck out Jason Bay to end the game. Buchholz ended up going 8 2/3 innings and giving up only two hits.
According to SI.com, Buchholz was included as part of a proposed December 7, 2006 trade with the Chicago White Sox to bring Jon Garland to the Astros. The trade, however, fell through when Buchholz failed his physical. Buchholz denies this, telling the Houston Chronicle that he hasn't had a physical since prior to the 2006 season.These rumors were cast off by White Sox general manager Ken Williams. 
- Named the Astros top prospect in 2004 by Baseball America.
- Named "Pitcher with Best Control" prior to the 2004 season by Baseball America.
- Ranked as the Astro's No. 7 prospect before the 2005 season.
- Florida State League Pitcher of the Year in 2002.
- Participated in American Legion baseball leagues.Template:2000s-baseball-pitcher-stub